INTRODUCTION
Use of cells for rapid analysis of chromosomal analysis and genomic
diagnostics continues to expand and increase in clinical and research
applications. Both direct interphase analysis using FISH and analysis of
chromosomes through karyotyping have proven to be successful in
providing relevant chromosomal information. With the expansion of these
analytical techniques increased throughput and decreased cost of sample
preparation and processing have become critical and important factors.
The BioDot automation and dispensing technology have been demonstrated
to enable sample and probe multiplexing along with miniaturizing sample
volumes, thereby reducing costs, increasing sample throughput, and
improving test accuracy.
The BioDot technology can be used for both spotting of cells or metaphase
chromosome preparations in nanoliter volumes for FISH and microscopic
analysis. After spotting of cell or chromosome preparations, the BioDot
technology can also be used to spot probe preparations onto samples in
reduced volumes, saving on reagent usage and enabling multiplexing of
samples and probes.
Click here for the application datasheet and
Click Here for the application poster.
Applications Flow Diagram